Paracetamol: The Risks of Underestimating a Common Medication

In a world where pain relief is often sought with a simple pill, paracetamol, also known as acetaminophen, has become a household name. Approved in the early 1950s, this chemical compound has risen to prominence as one of the most widely used and prescribed analgesics and antipyretics globally. However, the perceived innocuousness of this "miracle painkiller" belies a more complex and potentially hazardous reality.

In Morocco, paracetamol tops the list of the most consumed medications. Households routinely stockpile medicines containing this molecule, relying on it to alleviate migraines, flu symptoms, muscle aches, and menstrual cramps. It is often perceived as a universal solution for a multitude of ailments.

While paracetamol is an essential component of medical prescriptions aimed at reducing fever or alleviating mild to moderate pain, it remains a predominant choice for self-medication. Consequently, many individuals resort to its use without prior medical consultation, minimizing the risks associated with excessive consumption.

A study published in the British Journal of Clinical Pharmacology, titled "Long-term adverse effects of paracetamol," serves as a cautionary tale, warning against frequent overdosing and highlighting that the consequences can be more detrimental than acute intoxication, especially if hospital treatment is delayed. The study emphasizes that "regularly exceeding the recommended doses can be particularly harmful to the liver" and reveals that "among cases of toxicity related to accidental overdoses, 35% are due to the simultaneous intake of two or more products containing paracetamol."

Maha, a regular paracetamol consumer, recalls an instance when a doctor prescribed her a combination of two paracetamol-based medications to treat persistent fever. She now questions the potential risks of such a practice, which are often downplayed by healthcare professionals, according to testimonies gathered from several pharmacies.

Furthermore, in the treatment of moderate to severe pain, numerous formulations combining paracetamol and opioids have emerged. The study recommends heightened vigilance in all cases of hepatic pathologies, whether chronic or acute, with or without cirrhosis, as paracetamol use can be risky and requires particular attention from the prescriber.

In essence, while paracetamol remains a widely available and accessible medication, it is crucial to emphasize the importance of responsible use and awareness of the potential risks it may pose. Complacency in its consumption can have serious consequences, underscoring the need for caution and adherence to medical guidance.